InBOL leverages its multidisciplinary expertise, advanced facilities, and intellectual diversity to unravel the complexities of a wide range of diseases, driving innovation in healthcare and scientific research.
InBOL contributes to cancer research by enabling genetic barcoding approaches (structural and functional) that assist in distinguishing between different tumour subtypes and understanding cancer heterogeneity. By cataloguing genetic diversity within the Indian population, InBOL aids in identifying population-specific cancer markers and potential biomarkers for early diagnosis and prognosis.
The InBOL plays a crucial role in advancing research on rare diseases by building a repository of genetic and species-level diversity unique to Indian populations. This comprehensive genomic cataloguing is essential for identifying rare mutations and variants associated with inherited disorders that are often underdiagnosed due to the lack of region-specific genomic data. InBOL supports the development of diagnostic tools by linking barcoded genetic information (structural and functional) to clinical phenotypes, thereby improving early detection and diagnosis of orphan diseases. The initiative also enhances the scope of personalized medicine for rare disease patients by contributing population-specific genomic references that can inform targeted therapies and clinical decision-making.
In the domain of neurological disorders, InBOL facilitates research through the genetic mapping of neurodegenerative and neurodevelopmental conditions such as Parkinson’s disease, Alzheimer’s disease, epilepsy and ASD. By identifying specific genetic variants and patterns through DNA barcoding, InBOL enhances the understanding of the genetic basis of these conditions.
In the domain of metabolic diseases and disorders, InBOL facilitates research through advanced genomic methodologies, including DNA barcoding and molecular characterization. By analyzing genetic markers associated with conditions such as diabetes, thyroid disorders, and obesity, InBOL enhances the understanding of metabolic dysfunctions at a molecular level.
Through its One Health Genomics approach, InBOL contributes to precision medicine and therapeutic interventions, aiding in the identification of genetic predispositions and potential treatment strategies. Driven by its vision, InBOL has meticulously curated a comprehensive gene panel tailored to the diseases. The panel’s target selection is customizable, allowing clients to optimize structural and functional assessments based on specific research or diagnostic needs.
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